Research guide

Sample size and statistical power: a defensible justification

Justify sample size using the primary outcome, study design, plausible effect, power or precision; document attrition, clustering and sensitivity scenarios.

Illustrative charts and a data-analysis notebook in an academic workspace
Prepared by: Dr. Didgar Research Institute · Last revised: · 3 min read
Expected deliverables
  • Save calculation inputs, scenarios and the design rationale.
Decision workbook and example

Start with the primary analysis

Estimating a proportion, comparing means, fitting regression, cluster sampling and survival analysis have different requirements. A formula for a simple survey is not automatically appropriate for a complex model or a qualitative study. Specify the main outcome and design first.

Choose defensible assumptions

A power calculation needs an appropriate test, target effect, type-I error level, power, sidedness and allocation assumptions. Justify the effect using prior evidence, a meaningful threshold or a scientific scenario. Choosing it only to obtain a cheaper sample is not a scientific rationale.

Consider precision and design

The goal may be a sufficiently precise interval rather than a significance threshold. Repeated measurements, clustering and imbalanced data can require specialist methods or simulation. UCLA’s G*Power examples address particular tests; verify the match to your design independently.

Plan attrition and sensitivity

For n analyzable observations and anticipated attrition r, n/(1−r) is a simple recruitment approximation under explicit assumptions; round upward. Compare plausible effect and attrition scenarios. After observing results, do not substitute observed power for interval estimates or the original design justification.

Report enough to reproduce the calculation

Preserve software and version, test, every input, supporting assumptions and scenario results. Explain for which outcome and assumptions a proposed sample is adequate rather than declaring a universal number. Final study planning requires review of the actual design and resources.

Practical research checklist

  • Match the test to the research design.
  • Justify effect and precision.
  • Account for clustering and attrition.
  • Preserve inputs and sensitivity scenarios.

Worked case and implementation decisions

The following is a fictional teaching case. Do not use its numbers or wording as actual study findings.

Suppose an independently justified plan needs 100 analyzable observations and expects 15% attrition. The simple recruitment approximation 100/0.85 rounds up to 118; at 25% attrition it becomes 134. This arithmetic does not justify the initial 100 or account for clustering. Use scenarios to expose risk. If classes or repeated measures are involved, participants are not automatically independent observations. Preserve every calculation input and the effect rationale, not only the software’s final number.

Worked case and implementation decisions
StageTeaching exampleVerification question
GoalPower or precision for the main outcomeDoes it match the design?
Analyzable need100 is an exercise assumptionWas the actual need properly calculated?
15% attritionApproximate recruitment 118Is the rate justified?
25% attritionApproximate recruitment 134Is the harder scenario covered?
StructurePossible clusters or repetitionAre independence assumptions defensible?

Exercise output: Save calculation inputs, scenarios and the design rationale.

Sources and further reading

Official sources for verification and further reading

This guide supports research learning and planning; align implementation with the actual design and institutional requirements. Editorial policy
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